ncRNA name | apelin siRNA |
ncRNA Category | siRNA |
Disease name | choroidal neovascularization (CNV) |
Species | Homo sapiens |
Tissues/Cell_line | human umbilical vein endothelial cells (HUVECs) |
Methods | qPCR, immunohistochemistry, flow cytometry, siRNA transfection, qRT-PCR, alamar Blue assay |
Expression pattern | associated |
Functional description | Apelin small and interfering RNA (siRNA) suppressed proliferation of endothelial cells independently of vascular endothelial growth factor (VEGF) receptor 2 signaling, while VEGF increased expression of apelin and APJ in human umbilical vein endothelial cells. |
PubMed ID | 23722395 |
Year | 2013 |
Title | Laser-induced choroidal neovascularization in mice attenuated by deficiency in the apelin-APJ system. |
Drug-related ncRNA | NO |
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